Under 3% of the students at University of South Carolina-Upstate are registered with the college's disability services office.
| In-state | Out of state | |
| Cost of Attendance | $26,148 | $37,110 |
| Tuition | $11,583 | $22,545 |
| Room & Board (on-campus) | $9,328 | $9,328 |
| Books & Supplies | $1,600 | $1,600 |
| Transportation & Other | $3,637 | $3,637 |
| Percentage of students receiving some need-based aid | 98% | |
| Percentage of students receiving some Federal aid | 57% | |
| Percentage of students receiving some institutional aid | 19% | |
| Percentage of students with education loans | 73% |
University of South Carolina-Upstate's Admissions Page
In 2020, the average GPA of students admitted to University of South Carolina-Upstate was 3.70.
In 2020, 67% of applicants submitted SAT scores. Reported score ranges for admitted students:
| Score | Math | EBRW |
| 25th Percentile | 440 | 460 |
| 75th Percentile | 540 | 550 |
In 2020, 46% of applicants submitted ACT scores. Reported score ranges for admitted students:
| Score | Composite | Writing |
| 25th Percentile | 17 | - |
| 75th Percentile | 21 | - |
| Registered Nursing/Registered Nurse |
| Business Administration and Management, General |
| Criminal Justice/Law Enforcement Administration |
| Psychology, General |
| Liberal Arts and Sciences/Liberal Studies |