Under 3% of the students at Southern Illinois University-Edwardsville are registered with the college's disability services office.
| In-state | Out of state | |
| Cost of Attendance | $26,007 | $26,007 |
| Tuition | $12,219 | $12,219 |
| Room & Board (on-campus) | $9,881 | $9,881 |
| Books & Supplies | $933 | $933 |
| Transportation & Other | $2,974 | $2,974 |
| Percentage of students receiving some need-based aid | 89% | |
| Percentage of students receiving some Federal aid | 36% | |
| Percentage of students receiving some institutional aid | 46% | |
| Percentage of students with education loans | 61% |
SIUE's Admissions Page
In 2020, 48% of applicants submitted SAT scores. Reported score ranges for admitted students:
| Score | Math | EBRW |
| 25th Percentile | 510 | 500 |
| 75th Percentile | 610 | 610 |
In 2020, 51% of applicants submitted ACT scores. Reported score ranges for admitted students:
| Score | Composite | Writing |
| 25th Percentile | 21 | - |
| 75th Percentile | 27 | - |
| Registered Nursing/Registered Nurse |
| Business Administration and Management, General |
| Psychology, General |
| Biology/Biological Sciences, General |
| Criminal Justice/Safety Studies |
| Registered Nursing/Registered Nurse |
| Psychology, General |
| Biology/Biological Sciences, General |
| Computer and Information Sciences, General |
| Mechanical Engineering |
| Mass Communication/Media Studies |
| History, General |
| Speech Communication and Rhetoric |
| Geography |
| Sociology, General |