Purdue University-Main Campus competes in NCAA Division I-A.
| Name | Participants | |
|---|---|---|
| Men | Women | |
| Baseball | 35 | 0 |
| Basketball | 16 | 13 |
| All Track Combined | 95 | 130 |
| Football | 108 | 0 |
| Golf | 9 | 10 |
| Soccer | 0 | 27 |
| Softball | 0 | 19 |
| Swimming | 39 | 42 |
| Tennis | 9 | 9 |
| Volleyball | 0 | 17 |
| Wrestling | 30 | 0 |