Roanoke College competes in NCAA Division III (without football).
| Name | Participants | |
|---|---|---|
| Men | Women | |
| Baseball | 45 | 0 |
| Basketball | 16 | 14 |
| Field Hockey | 0 | 27 |
| Golf | 8 | 0 |
| Lacrosse | 48 | 24 |
| Soccer | 33 | 29 |
| Softball | 0 | 27 |
| Tennis | 11 | 13 |
| Track and Field, Indoor | 23 | 29 |
| Track and Field, Outdoor | 23 | 29 |
| Track and Field, X-Country | 11 | 11 |
| Volleyball | 0 | 11 |