East Tennessee State University competes in NCAA Division I-AA.
| Name | Participants | |
|---|---|---|
| Men | Women | |
| Baseball | 39 | 0 |
| Basketball | 16 | 13 |
| Football | 122 | 0 |
| Golf | 8 | 5 |
| Soccer | 34 | 26 |
| Softball | 0 | 25 |
| Tennis | 10 | 9 |
| Track and Field, Indoor | 36 | 41 |
| Track and Field, Outdoor | 36 | 41 |
| Track and Field, X-Country | 15 | 17 |
| Volleyball | 0 | 14 |