Pennsylvania State University-Main Campus competes in NCAA Division I-A.
| Name | Participants | |
|---|---|---|
| Men | Women | |
| Baseball | 35 | 0 |
| Basketball | 14 | 28 |
| All Track Combined | 124 | 133 |
| Fencing | 27 | 41 |
| Field Hockey | 0 | 26 |
| Football | 128 | 0 |
| Golf | 10 | 11 |
| Gymnastics | 19 | 15 |
| Ice Hockey | 26 | 31 |
| Lacrosse | 43 | 32 |
| Soccer | 26 | 29 |
| Softball | 0 | 24 |
| Swimming and Diving | 31 | 33 |
| Tennis | 13 | 13 |
| Volleyball | 17 | 20 |
| Wrestling | 32 | 0 |