Mercyhurst University competes in NCAA Division II (with football).
| Name | Participants | |
|---|---|---|
| Men | Women | |
| Baseball | 45 | 0 |
| Basketball | 19 | 14 |
| Field Hockey | 0 | 26 |
| Football | 98 | 0 |
| Golf | 10 | 8 |
| Ice Hockey | 29 | 27 |
| Lacrosse | 42 | 35 |
| Rowing | 29 | 24 |
| Soccer | 42 | 26 |
| Softball | 0 | 21 |
| Tennis | 11 | 9 |
| Track and Field, X-Country | 13 | 13 |
| Volleyball | 0 | 17 |
| Water Polo | 25 | 20 |
| Wrestling | 32 | 0 |