Keystone College competes in NCAA Division III (without football).
| Name | Participants | |
|---|---|---|
| Men | Women | |
| Baseball | 44 | 0 |
| Basketball | 19 | 15 |
| Field Hockey | 0 | 19 |
| Golf | 6 | 0 |
| Lacrosse | 19 | 19 |
| Soccer | 26 | 22 |
| Softball | 0 | 18 |
| Tennis | 8 | 9 |
| Track and Field, Indoor | 29 | 27 |
| Track and Field, Outdoor | 29 | 27 |
| Track and Field, X-Country | 6 | 9 |
| Volleyball | 0 | 15 |