Indiana University of Pennsylvania-Main Campus competes in NCAA Division II (with football).
| Name | Participants | |
|---|---|---|
| Men | Women | |
| Baseball | 29 | 0 |
| Basketball | 14 | 13 |
| All Track Combined | 92 | 97 |
| Field Hockey | 0 | 23 |
| Football | 89 | 0 |
| Golf | 7 | 0 |
| Lacrosse | 0 | 34 |
| Soccer | 0 | 25 |
| Softball | 0 | 20 |
| Swimming | 22 | 16 |
| Tennis | 0 | 7 |
| Volleyball | 0 | 16 |