Centre College competes in NCAA Division III (with football).
| Name | Participants | |
|---|---|---|
| Men | Women | |
| Baseball | 28 | 0 |
| Basketball | 17 | 21 |
| All Track Combined | 71 | 66 |
| Field Hockey | 0 | 20 |
| Football | 115 | 0 |
| Golf | 15 | 6 |
| Lacrosse | 28 | 21 |
| Soccer | 35 | 31 |
| Softball | 0 | 17 |
| Swimming and Diving | 18 | 17 |
| Tennis | 10 | 15 |
| Volleyball | 0 | 15 |