University of Illinois at Springfield competes in NCAA Division II (without football).
| Name | Participants | |
|---|---|---|
| Men | Women | |
| Baseball | 36 | 0 |
| Basketball | 14 | 12 |
| Golf | 11 | 11 |
| Soccer | 27 | 24 |
| Softball | 0 | 18 |
| Tennis | 9 | 6 |
| Track and Field, Indoor | 0 | 11 |
| Track and Field, X-Country | 11 | 7 |
| Volleyball | 0 | 17 |